SAM-E's many uses.
SAM-E has been used successfully to treat depression in Europe for the past 20 years. In some European countries SAM-E is used more frequently than the antidepressant Prozac®. It can also be given intravenously for more pronounced effects. The use of SAM-E, either in tablet or inintravenous form, is expensive but many people who can afford to use it report significant and worthwhile benefits.
· Fibromyalgia: SAM-E has been shown to improve symptoms of pain, fatigue, morning stiffness, and mood in patients with fibromyalgia.
· Liver Disease: SAM-E is highly concentrated in liver tissue. Clinical studies indicate that SAM-E treatment can reverse hepatic glutathione depletion in patients with liver disease; improve survival or delay liver transplantation in patients with alcoholic liver cirrhosis as well as reduce biochemical parameters of intrahepatic cholestasis, such as bilirubin and bile salts, and subjective symptoms, such as pruritis, fatigue, and general discomfort.
· Osteoarthritis: While it was being used to treat patients for mood disorders, SAM-E was found to have beneficial effects on osteoarthritis . The Arthritis Foundation's Guide to Alternative Therapies notes that "SAM-E is a promising treatment worth trying for pain relief". A significant amount of research supports the use of SAM-E in treating osteoarthritis. SAM-E has been shown to be at least as effective as NSAIDs, if not more so, without causing the gastrointestinal side effects associated with NSAID use.
· Migraine: Studies suggest that SAM-E may help in the treatment of migraines with less side effects than current treatments.
· ADD: Doctors are currently studying the effects of SAM-E on Attention Deficit Disorder. They theorize that with the calming, anti-stress effects, SAM-E may be able to bring some measure of relief from ADD symptoms.
· Asthma: Since stress is often a major factor in the frequency of asthmatic attacks doctors believe that SAM-E's stress reducing properties may help in preventing asthma attacks.
· Parkinson's disease: Studies are still being conducted on the possible benefit of SAM-E in the treatment of Parkinson's disease.
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